Isabelle Bourdeau Selected Research

Adrenocortical Adenoma (Disease, Conn's)

12/2021	Loss of KDM1A in GIP-dependent primary bilateral macronodular adrenal hyperplasia with Cushing's syndrome: a multicentre, retrospective, cohort study.
2/2019	Exacerbation of Cushing's syndrome during pregnancy: stimulation of a cortisol-secreting adrenocortical adenoma by ACTH originating from the foeto-placental unit.
9/2011	Identification of genetic alterations of AXIN2 gene in adrenocortical tumors.
7/2011	Characterization of differential gene expression in adrenocortical tumors harboring beta-catenin (CTNNB1) mutations.
9/2008	Detection of somatic beta-catenin mutations in primary pigmented nodular adrenocortical disease (PPNAD).
2/2008	Frequent mutations of beta-catenin gene in sporadic secreting adrenocortical adenomas.
6/2007	Adrenocorticotropic hormone-independent Cushing's syndrome.
6/2002	Cyclic AMP-dependent signaling aberrations in macronodular adrenal disease.

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Isabelle Bourdeau Research Topics

Disease

29	Cushing Syndrome 06/2022 - 08/2003
29	Hyperplasia 01/2022 - 06/2002
23	Neoplasms (Cancer) 01/2022 - 05/2002
16	Acth-Independent Macronodular Adrenal Hyperplasia 01/2015 - 06/2002
13	Adenoma (Adenomas) 01/2021 - 01/2004
12	Hyperaldosteronism (Conn Syndrome) 08/2022 - 07/2010
8	Adrenocortical Adenoma (Disease, Conn's) 12/2021 - 06/2002
7	Adrenocortical Carcinoma 01/2022 - 02/2008
6	Pheochromocytoma 04/2021 - 05/2014
6	Pituitary ACTH Hypersecretion 01/2020 - 08/2005
6	Carney Complex 06/2009 - 06/2002
5	Carcinoma (Carcinomatosis) 09/2011 - 06/2002
4	Paraganglioma (Paragangliomas) 04/2021 - 05/2014
3	Neoplasm Metastasis (Metastasis) 01/2022 - 09/2005
3	Adrenal Insufficiency (Adrenal Gland Hypofunction) 01/2021 - 08/2018
3	Adrenal incidentaloma 01/2020 - 06/2014
2	Adrenal Cortex Neoplasms (Adrenocortical Cancer) 03/2020 - 02/2008
2	Congenital Adrenal Hyperplasia (Hyperplasia, Congenital Adrenal) 01/2020 - 08/2018
2	Myelolipoma 01/2019 - 08/2018
2	Hypoglycemia (Reactive Hypoglycemia) 01/2016 - 02/2009
2	Polyostotic Fibrous Dysplasia (McCune Albright Syndrome) 04/2012 - 07/2004
2	Carcinogenesis 07/2011 - 09/2008
1	Hypersensitivity (Allergy) 08/2022
1	Abdominal Pain (Pain, Abdominal) 01/2021
1	Hyponatremia 01/2021
1	Hypotension (Low Blood Pressure) 01/2021
1	Hyperkalemia 01/2021
1	Fatigue 01/2021
1	Weight Loss (Weight Reduction) 01/2021
1	Adrenocortical Hyperfunction (Adrenal Gland Hyperfunction) 01/2020
1	Glucocorticoid Receptor Deficiency 01/2020
1	Hypertension (High Blood Pressure) 02/2019
1	Atrophy 02/2019
1	Gestational Diabetes (Gestational Diabetes Mellitus) 02/2019
1	Hyperglycemia 01/2019
1	Infections 08/2018
1	Endocrine System Diseases (Endocrine Diseases) 08/2018
1	Hemorrhage 08/2018
1	Oxyphilic Adenoma (Oncocytoma) 01/2018
1	Panic Disorder (Panic Attack) 01/2018
1	Takotsubo Cardiomyopathy 10/2017
1	Cardiomyopathies (Cardiomyopathy) 10/2017

Drug/Important Bio-Agent (IBA)

31	Hydrocortisone (Cortisol)FDA LinkGeneric 06/2022 - 06/2002
29	Adrenocorticotropic Hormone (ACTH)FDA Link 08/2022 - 05/2002
19	Hormones (Hormone)IBA 01/2022 - 06/2002
14	AldosteroneIBA 08/2022 - 02/2008
8	GlucocorticoidsIBA 03/2020 - 07/2004
6	LigandsIBA 01/2018 - 01/2004
5	gastric inhibitory polypeptide receptorIBA 12/2021 - 08/2005
5	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 12/2021 - 06/2002
5	SteroidsIBA 01/2020 - 10/2004
5	DNA (Deoxyribonucleic Acid)IBA 09/2016 - 07/2004
5	Proteins (Proteins, Gene)FDA Link 07/2011 - 09/2003
5	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 06/2009 - 06/2002
4	CatecholaminesIBA 01/2018 - 02/2004
3	Mitotane (Lysodren)FDA Link 04/2021 - 03/2016
3	Insulin (Novolin)FDA Link 02/2019 - 02/2009
3	CateninsIBA 01/2018 - 07/2011
3	ReninIBA 01/2018 - 07/2010
3	Vasopressins (Vasopressin)IBA 01/2016 - 02/2004
3	Fumarate Hydratase (Fumarase)IBA 05/2014 - 06/2005
3	beta CateninIBA 07/2011 - 02/2008
3	Complementary DNA (cDNA)IBA 09/2008 - 02/2004
2	Dexamethasone (Maxidex)FDA LinkGeneric 08/2022 - 08/2003
2	AndrogensIBA 01/2020 - 09/2016
2	Type 2 Melanocortin ReceptorIBA 02/2019 - 06/2014
2	pasireotideIBA 01/2019 - 12/2014
2	Serotonin (5 Hydroxytryptamine)IBA 01/2018 - 11/2004
2	AngiotensinsIBA 01/2018 - 01/2016
2	Ion Channels (Ion Channel)IBA 01/2018 - 01/2016
2	Luteinizing Hormone (Lutropin)FDA LinkGeneric 01/2018 - 11/2004
2	Angiotensin IIIBA 01/2018 - 11/2004
2	GTP-Binding Proteins (G-Protein)IBA 01/2018 - 01/2004
2	Peptides (Polypeptides)IBA 11/2004 - 02/2004
1	Prednisone (Sone)FDA LinkGeneric 08/2022
1	Contrast MediaIBA 08/2022
1	IodineIBA 08/2022
1	Ligases (Synthetase)IBA 01/2022
1	UbiquitinIBA 01/2022
1	Biomarkers (Surrogate Marker)IBA 04/2021
1	Chromogranin AIBA 04/2021
1	Tumor Biomarkers (Tumor Markers)IBA 04/2021
1	SaltsIBA 01/2021
1	Cosyntropin (Cortrosyn)FDA LinkGeneric 01/2021
1	Pharmaceutical PreparationsIBA 03/2020
1	Dehydroepiandrosterone (DHEA)IBA 01/2020
1	Messenger RNA (mRNA)IBA 02/2019
1	Sunitinib (Sutent)FDA Link 01/2019
1	Biological ProductsIBA 08/2018
1	LHRH Receptors (Gonadotropin-Releasing Hormone Receptor)IBA 01/2018
1	Cyclic AMP (AMP, Cyclic)IBA 01/2018
1	Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric 01/2018
1	Venlafaxine Hydrochloride (Effexor)FDA LinkGeneric 01/2018
1	Gonadotropin-Releasing Hormone (GnRH)FDA Link 01/2018
1	3-Iodobenzylguanidine (Iobenguane)IBA 10/2017

Therapy/Procedure

6	Therapeutics 01/2022 - 06/2014
6	Adrenalectomy 12/2021 - 01/2004
1	Premedication 08/2022
1	Cytoreduction Surgical Procedures 01/2022
1	Precision Medicine 08/2018